Join Us

Join the Sai Ma Lab

Multiple postdoctoral and student positions are available in the Ma Lab in the Department of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai in New York City. We are looking for curious, motivated scientists interested in single-cell and spatial genomics, epigenetics, gene regulation, and disease biology.

Email Dr. Sai Ma

Prospective Students

Prospective graduate students interested in rotating in the lab are encouraged to contact Dr. Sai Ma directly.

What We Do

Our lab develops experimental and computational technologies to investigate epigenetic mechanisms of gene regulation at single-cell resolution across dynamic cell-state transitions. We are interested in understanding how regulatory programs shape normal development and how these programs are perturbed in aging and disease.
We develop scalable single-cell and spatial multi-omic technologies to jointly measure DNA methylation, chromatin accessibility, gene expression, and genome organization. We also build computational methods to integrate these measurements and reconstruct regulatory mechanisms underlying cell fate decisions.
Current research directions include technology development, gene regulation, cell-fate mapping, hematopoiesis, aging, neurodegeneration, and cancer.

Your Qualifications

Postdoctoral candidates should hold a PhD or MD/PhD in cell biology, molecular biology, genetics, genomics, bioengineering, biomedical engineering, computational biology, or a related field.
Candidates should be able to work independently and communicate effectively with collaborators from diverse experimental and computational backgrounds. Prior experience with next-generation sequencing, single-cell genomics, molecular biology, or programming is helpful but not required.
Applicants with BA/BS or MA/MS degrees may also be considered for Research Associate positions.

How to Apply

Interested applicants should email Dr. Sai Ma with:
1. A brief summary of research interests 2. A CV including a complete publication list 3. Names and contact information for three references

Life at Mount Sinai

Mount Sinai provides a highly collaborative research environment with extensive shared facilities and strong programs in genomics, stem cell biology, cancer, neuroscience, and computational biology.
Our lab aims to provide a supportive and collaborative training environment, with opportunities to develop both experimental and computational expertise. Trainees are encouraged to present their work at national and international conferences and to pursue fellowship opportunities.
Postdoctoral fellows receive competitive salary and benefits, and eligible incoming fellows may apply for Mount Sinai housing within walking distance of the medical center.