Students
Prospective Students
Prospective graduate students interested in rotating in the lab are encouraged to contact Dr. Sai Ma directly.
Research
What We Do
Our lab develops experimental and computational technologies to investigate epigenetic mechanisms of gene regulation at single-cell resolution across dynamic cell-state transitions. We are interested in understanding how regulatory programs shape normal development and how these programs are perturbed in aging and disease.
We develop scalable single-cell and spatial multi-omic technologies to jointly measure DNA methylation, chromatin accessibility, gene expression, and genome organization. We also build computational methods to integrate these measurements and reconstruct regulatory mechanisms underlying cell fate decisions.
Current research directions include technology development, gene regulation, cell-fate mapping, hematopoiesis, aging, neurodegeneration, and cancer.
Candidates
Your Qualifications
Postdoctoral candidates should hold a PhD or MD/PhD in cell biology, molecular biology, genetics, genomics, bioengineering, biomedical engineering, computational biology, or a related field.
Candidates should be able to work independently and communicate effectively with collaborators from diverse experimental and computational backgrounds. Prior experience with next-generation sequencing, single-cell genomics, molecular biology, or programming is helpful but not required.
Applicants with BA/BS or MA/MS degrees may also be considered for Research Associate positions.
Apply
How to Apply
Interested applicants should email Dr. Sai Ma with:
1. A brief summary of research interests 2. A CV including a complete publication list 3. Names and contact information for three references
Mount Sinai
Life at Mount Sinai
Mount Sinai provides a highly collaborative research environment with extensive shared facilities and strong programs in genomics, stem cell biology, cancer, neuroscience, and computational biology.
Our lab aims to provide a supportive and collaborative training environment, with opportunities to develop both experimental and computational expertise. Trainees are encouraged to present their work at national and international conferences and to pursue fellowship opportunities.
Postdoctoral fellows receive competitive salary and benefits, and eligible incoming fellows may apply for Mount Sinai housing within walking distance of the medical center.